LIF

白血病抑制因子（LIF）屬于IL-6超家族的細胞因子。LIF可在不同的細胞中表達，包括活化的T細胞、單核細胞、膠質細胞、肝臟成纖維細胞、骨髓基質細胞、胚胎干細胞、胸腺上皮細胞和許多其他細胞。LIF的作用是通過一個高親和力的受體復合物介導的，該復合物由一個低親和力的LIFRβ（也稱為LIFR）和一個高親和力的亞單位gp130組成，從而激活STAT、p21ras/MAP和PI-3信號途徑。LIF作為具有多種生物功能的細胞因子，可參與骨髓性白血病細胞的造血分化，腎臟發育過程中間質向上皮的轉化。在癌癥中也有強大的功能，參與了腫瘤生長和進展的一些關鍵過程，包括免疫耐受、PNI、化療和放射抗性、癌癥干細胞樣表型維持、EMT和TME發展。

Recombinant Human LIF 活性蛋白實驗驗證數據

High Purity Validated by SDS-PAGE

CSB-MP006254HU(F1) is detected by Mouse anti-6*His monoclonal antibody.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized human LIF at 2 μg/ml can bind human LIFR (CSB-MP012929HUi9), the EC₅₀ is 22.58-30.24 ng/ml.

LIF Antibody

LIF Protein

LIF ELISA Kit

LIF Antibodies

LIF for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA012928ESR2HU	LIF Antibody	Human	ELISA
CSB-PA004761	LIF Antibody	Human	WB, ELISA
CSB-PA198481	LIF Antibody	Human,Mouse,Rat	ELISA,IHC

LIF Proteins

LIF Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-EP012928HU CSB-BP012928HU CSB-EP012928HU-B	Recombinant Human Leukemia inhibitory factor (LIF)	E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-AP002221HU	Recombinant Human Leukemia inhibitory factor protein (LIF)	E.Coli
CSB-AP004001HU	Recombinant Human Leukemia inhibitory factor (LIF) (Active)	E.coli
CSB-MP012928HUd9	Recombinant Human Leukemia inhibitory factor (LIF) (Active)	Mammalian cell
CSB-MP012928HU	Recombinant Human Leukemia inhibitory factor (LIF) (Active)	Mammalian cell
CSB-YP012928HU	Recombinant Human Leukemia inhibitory factor (LIF)	Yeast
CSB-MP012928HU-WD	Recombinant Human Leukemia inhibitory factor (LIF) (Active)	Mammalian cell

LIF Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-EP012928RA CSB-BP012928RA CSB-EP012928RA-B	Recombinant Rat Leukemia inhibitory factor (Lif)	E.coli Baculovirus In Vivo Biotinylation in E.coli

LIF Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-BP012928MO CSB-EP012928MO-B	Recombinant Mouse Leukemia inhibitory factor (Lif)	Baculovirus In Vivo Biotinylation in E.coli

LIF Proteins for Mustela vison (American mink) (Neovison vison)

產品貨號	產品名稱	來源
CSB-YP528926MVE CSB-EP528926MVE CSB-BP528926MVE CSB-MP528926MVE CSB-EP528926MVE-B	Recombinant Mustela vison Leukemia inhibitory factor (LIF)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

LIF Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP637735BO CSB-EP637735BO CSB-BP637735BO CSB-MP637735BO CSB-EP637735BO-B	Recombinant Bovine Leukemia inhibitory factor (LIF)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli