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APMAP Monoclonal Antibody

  • 中文名稱：
    APMAP Monoclonal Antibody
  • 貨號：
    CSB-MA943823
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of APMAP expression in HT-1080 cells using APMAP antibody. Green, isotype control; red, APMAP.
    • Immunocytochemical staining of HT-1080 cells with APMAP antibody. Nuclei were stained blue with DAPI; APMAP was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
    • Western blotting analysis using APMAP antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with APMAP antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Mouse anti-Homo sapiens (Human) APMAP Monoclonal antibody
  • Uniprot No.：
  • 基因名：
    APMAP
  • 別名：
    APMAP; Adipocyte Plasma Membrane Associated Protein; C20orf3; BSCv; Adipocyte Plasma Membrane-Associated Protein; Protein BSCv; Chromosome 20 Open Reading Frame 3
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human APMAP protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    21G5
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2500
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.
  • 基因功能參考文獻(xiàn)：
    1. These data suggest that APMAP is a novel regulator of extracellular matrix components, and establish that APMAP is a potential target to mitigate obesity-associated insulin resistance. PMID: 28559441
    2. APMAP is an endogenous suppressor of Abeta production in the brain. PMID: 25180020
    3. C20orf3 mapping at chromosome 20p11 is associated with hepatic-specific metastasis in patients with colorectal cancer. PMID: 22267596
    4. characterization of the gene product of open reading frame 3 encoded at human chromosome 20 (C20orf3), which represents a member of the lactonohydrolase super family PMID: 18513186
  • 亞細(xì)胞定位：
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Strictosidine synthase family
  • 組織特異性：
    Liver, glomerular and tubular structures of the kidney, endothelial cells, arterial wall and pancreatic islets of Langerhans (at protein level). Found ubiquitously in adult as well as in embryonic tissues. In adult tissue, the highest expression is found
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13238

    OMIM: 615884

    KEGG: hsa:57136

    STRING: 9606.ENSP00000217456

    UniGene: Hs.472330