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VPS4B

Vacuolar protein sorting-associated protein 4B is a protein in humans that is encoded by VPS4B gene. Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.

VPS4B Antibodies

VPS4B for Homo sapiens (Human)

VPS4B Proteins

VPS4B Proteins for Mus musculus (Mouse)

VPS4B Proteins for Homo sapiens (Human)

VPS4B Proteins for Bos taurus (Bovine)

VPS4B Proteins for Pongo abelii (Sumatran orangutan)