VPS37A
VPS37A，是一種屬于泛素連接酶E3泛素連接酶家族的成員，在細(xì)胞內(nèi)自噬過程中發(fā)揮關(guān)鍵作用。該蛋白參與自噬體與溶酶體的結(jié)合，促進(jìn)自噬體的成熟和降解過程。VPS37A蛋白的異常表達(dá)與多種疾病相關(guān)，如阿爾茨海默病、帕金森病和癌癥等。針對VPS37A蛋白的藥物研發(fā)主要集中在自噬抑制劑領(lǐng)域，旨在通過調(diào)節(jié)自噬過程來治療相關(guān)疾病。目前，已有一些自噬抑制劑進(jìn)入臨床試驗(yàn)階段，顯示出良好的治療效果。例如，一些小分子抑制劑能夠特異性地抑制VPS37A蛋白的活性，從而阻止自噬體的形成和降解，進(jìn)而抑制腫瘤細(xì)胞的生長和擴(kuò)散。此外，一些靶向VPS37A蛋白的抗體藥物也在研發(fā)中，有望為相關(guān)疾病的治療提供新的選擇。
熱銷產(chǎn)品
VPS37A Antibody (CSB-PA567081)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA567081(VPS37A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA567081(VPS37A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal liver tissue and hela cell, Primary antibody: CSB-PA567081(VPS37A Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
VPS37A Antibodies
VPS37A for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA025906GA01HU | VPS37A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA567081 | VPS37A Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA256766 | VPS37A Antibody | Human,Mouse | ELISA,WB,IHC |
VPS37A Proteins
VPS37A Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP818779HU CSB-EP818779HU CSB-BP818779HU CSB-MP818779HU CSB-EP818779HU-B |
Recombinant Human Vacuolar protein sorting-associated protein 37A (VPS37A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
