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VPS37A

VPS37A,是一種屬于泛素連接酶E3泛素連接酶家族的成員,在細胞內自噬過程中發揮關鍵作用。該蛋白參與自噬體與溶酶體的結合,促進自噬體的成熟和降解過程。VPS37A蛋白的異常表達與多種疾病相關,如阿爾茨海默病、帕金森病和癌癥等。針對VPS37A蛋白的藥物研發主要集中在自噬抑制劑領域,旨在通過調節自噬過程來治療相關疾病。目前,已有一些自噬抑制劑進入臨床試驗階段,顯示出良好的治療效果。例如,一些小分子抑制劑能夠特異性地抑制VPS37A蛋白的活性,從而阻止自噬體的形成和降解,進而抑制腫瘤細胞的生長和擴散。此外,一些靶向VPS37A蛋白的抗體藥物也在研發中,有望為相關疾病的治療提供新的選擇。

熱銷產品

VPS37A Antibody (CSB-PA567081)

驗證數據

CSB-PA567081

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA567081(VPS37A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA567081

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA567081(VPS37A Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA567081

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal liver tissue and hela cell, Primary antibody: CSB-PA567081(VPS37A Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds

VPS37A Antibodies

VPS37A for Homo sapiens (Human)

VPS37A Proteins

VPS37A Proteins for Homo sapiens (Human)