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SPTLC3

SPTLC3,即絲氨酸棕櫚酰轉移酶長鏈堿基亞基3,別名LCB3、SPT3、LCB3、LCB2B、SPT3、hLCB2b、SPTLC2L。SPTLC3是絲氨酸棕櫚酰轉移酶復合體的一個亞基,該復合體催化鞘脂生物合成中的限速步驟。該亞基代謝月桂酰輔酶A和肉豆蔻酰輔酶A,生成C14和C16鞘氨醇堿基。SPTLC3對于鞘脂的合成至關重要,鞘脂是細胞膜的重要組成部分,并參與多種細胞信號傳導過程,包括細胞凋亡、細胞增殖、細胞遷移和炎癥反應。異常的SPTLC3表達與多種疾病相關,包括心血管疾病、腫瘤和神經退行性疾病。

熱銷產品

SPTLC3 Antibody (CSB-PA865142LA01HU)

驗證數據

CSB-PA865142LA01HU

Western blot
All lanes: SPTLC3 antibody at 0.2µg/ml
Lane 1: Mouse kidney tissue
Lane 2: U87 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 63, 20 kDa
Observed band size: 63 kDa

CSB-PA865142LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA865142LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

CSB-PA865142LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA865142LA01HU at dilution of 1:100

CSB-PA865142LA01HU

Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA865142LA01HU at dilution of 1:100

SPTLC3 Antibodies

SPTLC3 for Homo sapiens (Human)

SPTLC3 Proteins

SPTLC3 Proteins for Homo sapiens (Human)