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PVALB

PVALB,即小清蛋白(Parvalbumin)。它是一種低分子量的鈣結合蛋白,分子量大約在10-12.5 kDa之間,結構上與鈣調蛋白和肌鈣蛋白C有關。PVALB在快肌纖維中的含量特別高,但也在其他組織和器官如魚類的大腦和生殖腺中表達。PVALB的作用機制涉及調節肌肉中的鈣離子轉換,特別是在快肌纖維中,它幫助控制肌肉收縮的速度和力度。在生物學意義上,PVALB在多種生物過程中發揮作用,包括神經遞質釋放、肌肉收縮以及作為魚類中的主要過敏原。超過95%的魚類引起的食品過敏是由PVALB蛋白引起的。此外,PVALB還可能作為肥胖治療的潛在新靶點,通過影響M2型巨噬細胞來調節能量消耗和產熱。

熱銷產品

Recombinant Mouse Parvalbumin alpha (Pvalb)

驗證數據

SDS
CSB-EP019092MO SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PVALB Antibody

驗證數據

IF
CSB-PA019092HA01HU IF-1

Immunofluorescence staining of U251 cells with CSB-PA019092HA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

WB
CSB-PA019092HA01HU WB

Western Blot
Positive WB detected in: Mouse brain tissue, Mouse kidney tissue
All lanes: PVALB antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 13 kDa
Observed band size: 13 kDa

IF
CSB-PA019092HA01HU IF-2

Immunofluorescent analysis of HepG2 cells using CSB-PA019092HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

IHC
CSB-PA019092HA01HU IHC-1

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA019092HA01HU at dilution of 1:100

IHC
CSB-PA019092HA01HU IHC-2

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA019092HA01HU at dilution of 1:100


PVALB Antibodies

PVALB for Homo sapiens (Human)

PVALB Proteins

PVALB Proteins for Homo sapiens (Human)



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