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NPPB

NPPB,全稱(chēng)為腦鈉肽B型,是一種由心室肌細(xì)胞分泌的心臟激素,主要在心室壁壓力和容量增加時(shí)產(chǎn)生。它也被稱(chēng)為BNP(B型利鈉肽),具有利尿、排鈉、血管舒張、抑制腎素和醛固酮分泌等作用,對(duì)心血管系統(tǒng)的穩(wěn)態(tài)維持至關(guān)重要。NPPB在心力衰竭患者中是重要的預(yù)后指標(biāo),其水平升高通常預(yù)示著心功能不全。此外,NPPB還具有抗菌和抗真菌活性,其基因突變與骨質(zhì)疏松癥的發(fā)生有關(guān)。在藥物研發(fā)方面,針對(duì)NPPB及其受體的藥物已被廣泛應(yīng)用于心力衰竭的治療,如利鈉肽類(lèi)藥物和拮抗劑。近年來(lái),隨著對(duì)NPPB生物學(xué)功能的深入研究,其在心血管疾病、骨質(zhì)疏松等領(lǐng)域的治療潛力正逐步被挖掘。

熱銷(xiāo)產(chǎn)品

Recombinant Human natriuretic peptide B (NPPB), partial (CSB-EP016021HU(A5))

驗(yàn)證數(shù)據(jù)

CSB-EP016021HU(A5)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NPPB Recombinant Monoclonal Antibody (CSB-RA016021MA1HU)

驗(yàn)證數(shù)據(jù)

CSB-RA016021MA1HU

Overlay Peak curve showing 786-O cells stained with CSB-RA016021MA1HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was Fluorescein (FITC) AffiniPure Goat Anti-Human IgG, Fcγ fragment specific at 1:200 dilution for 35min at 4℃.Control antibody (green line) was human IgG1 (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human brain natriuretic peptide,BNP ELISA Kit (CSB-E07970h)

驗(yàn)證數(shù)據(jù)

CSB-E07970h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E07970h

規(guī)格:96T/48T

靈敏度:23.43 pg/mL

檢測(cè)范圍:93.75 pg/mL-6000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

NPPB Antibodies

NPPB for Homo sapiens (Human)

NPPB Proteins

NPPB Proteins for Bos taurus (Bovine)

NPPB Proteins for Rattus norvegicus (Rat)

NPPB Proteins for Mus musculus (Mouse)

NPPB Proteins for Sus scrofa (Pig)

NPPB Proteins for Ovis aries (Sheep)

NPPB Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

NPPB Proteins for Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica)

NPPB Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

NPPB Proteins for Felis catus (Cat) (Felis silvestris catus)

NPPB Proteins for Homo sapiens (Human)

NPPB ELISA Kit

NPPB ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

NPPB ELISA Kit for Homo sapiens (Human)

NPPB ELISA Kit for Sus scrofa (Pig)

NPPB ELISA Kit for Rattus norvegicus (Rat)

NPPB ELISA Kit for Mus musculus (Mouse)



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