ELAPOR1
ELAPOR1,全稱為Endosome-Lysosome Associated Apoptosis And Autophagy Regulator 1,常見別名為EIG121、KIAA1324。該蛋白是一種跨膜蛋白,由雌激素誘導(dǎo)表達(dá),主要與內(nèi)體-溶酶體區(qū)室相關(guān),可能在自噬和細(xì)胞增殖中發(fā)揮重要作用。在不利條件下,如饑餓和接觸細(xì)胞毒性劑,ELAPOR1可通過上調(diào)自噬途徑保護(hù)細(xì)胞免受死亡。近年來,研究發(fā)現(xiàn)ELAPOR1在精子頂體的形成中扮演關(guān)鍵角色,作為銅離子依賴的新型膜拴系因子,驅(qū)動(dòng)PAVs融合形成精子頂體,為男性生殖功能提供了新的研究視角。此外,ELAPOR1與多種疾病相關(guān),包括神經(jīng)退行性疾病和癌癥。在藥物研發(fā)方面,已有公司開始生產(chǎn)ELAPOR1蛋白,為相關(guān)疾病的研究和診斷提供重要工具。未來,針對ELAPOR1的藥物研發(fā)可能為治療這些疾病帶來新的希望。
熱銷產(chǎn)品
KIAA1324 Antibody (CSB-PA965968)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA965968(KIAA1324 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA965968(KIAA1324 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
ELAPOR1 Antibodies
ELAPOR1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA965968 | KIAA1324 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA064264 | KIAA1324 Antibody | Human,Mouse | ELISA,IHC |
ELAPOR1 Proteins
ELAPOR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP764944HU CSB-EP764944HU CSB-BP764944HU CSB-MP764944HU CSB-EP764944HU-B |
Recombinant Human Endosome/lysosome-associated apoptosis and autophagy regulator 1 (ELAPOR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |






