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CLEC2D

CLEC2D,全稱為C-type lectin domain family 2 member D,常見別名包括CLAX、LLT1、OCIL等。該蛋白主要位于細胞膜外基質,具有抑制破骨細胞形成、調節干擾素-γ釋放、結合高分子量硫酸化糖胺聚糖等多種功能。CLEC2D蛋白在多種組織中表達,包括胎兒心臟、腦、肺、軟骨細胞等,并在成人脾細胞、胸腺細胞、淋巴結細胞等組織中也有檢測到。研究表明,CLEC2D蛋白與腫瘤免疫治療密切相關,其在惡性腦腫瘤中發揮重要作用。通過阻斷CLEC2D與CD161受體的相互作用,可以增強T細胞對腫瘤細胞的殺傷作用,提高動物的存活率。此外,CLEC2D蛋白還與黑色素瘤、肺癌、結腸癌和肝癌等多種癌癥相關。目前,針對CLEC2D蛋白的藥物研發正在積極進行中,有望為癌癥患者提供新的治療策略。

熱銷產品

CLEC2D Antibody (CSB-PA254797)

驗證數據

CSB-PA254797

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA254797(CLEC2D Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA254797

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA254797(CLEC2D Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)

Human C-type lectin domain family 2 member D(CLEC2D) ELISA kit (CSB-EL005528HU)

驗證數據

CSB-EL005528HU 標準曲線

貨號:CSB-EL005528HU

規格:96T/48T

靈敏度:7.81 pg/mL

檢測范圍:31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CLEC2D Antibodies

CLEC2D for Homo sapiens (Human)

CLEC2D Proteins

CLEC2D Proteins for Homo sapiens (Human)

CLEC2D ELISA Kit

CLEC2D ELISA Kit for Homo sapiens (Human)