国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. PRPF4 Recombinant Monoclonal Antibody

PRPF4 Recombinant Monoclonal Antibody

  • 中文名稱：
    PRPF4 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA959642A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of PRPF4 expression in HepG2 cells using PRPF4 antibody. Green, isotype control; red, PRPF4.
    • Immunocytochemical staining of HepG2 cells with PRPF4 antibody. Nuclei were stained blue with DAPI; PRPF4 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar, 20 μm.
    • Western blotting analysis using PRPF4 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with PRPF4 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PRPF4
  • 別名：
    Pre-MRNA Processing Factor 4; PRP4; U4/U6 Small Nuclear Ribonucleoprotein Prp4; SNRNP60; HPRP4P; Prp4p; HPRP4; PRP4/STK/WD Splicing Factor; U4/U6 SnRNP 60 KDa Protein; WD Splicing Factor Prp4; PRP4 Homolog; PRP4 Pre-MRNA Processing Factor 4 Homolog (Yeast); PRP4 Pre-MRNA Processing Factor 4 Homolog; HPrp4; RP70
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human PRPF4 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    21C7
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
  • 基因功能參考文獻：
    1. The p.R192H variant of PRPF4 represents a functional null allele which compromises the function of the tri-snRNP, reinforcing the notion that this spliceosomal particle is of crucial importance in the physiology of the retina. PMID: 25383878
    2. PRPF4 missense mutations is associated with autosomal dominant retinitis pigmentosa. PMID: 24419317
    3. the requirement of enzymatic activity of PRP4 in regulating cancer cell growth and identified an array of potential novel substrates through orthogonal proteomics approaches PMID: 24003220
    4. interaction between Hprp3p and Hprp4p PMID: 11971898
    5. PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores. PMID: 17998396
    6. PRP-4 belongs to the serine/threonine protein kinase family, plays a role in pre-mRNA splicing and cell mitosis, and interacts with CLK1 PMID: 18687998

    顯示更多

    收起更多

  • 相關疾病：
    Retinitis pigmentosa 70 (RP70)
  • 亞細胞定位：
    Nucleus. Nucleus speckle.
  • 數據庫鏈接：

    HGNC: 17349

    OMIM: 607795

    KEGG: hsa:9128

    STRING: 9606.ENSP00000363313

    UniGene: Hs.744014



主站蜘蛛池模板： 濮阳市| 和田县| 黎川县| 吉林市| 天祝| 繁昌县| 通榆县| 射阳县| 永寿县| 孝昌县| 上饶县| 策勒县| 淮北市| 宽城| 芮城县| 阳信县| 津市市| 甘德县| 泽库县| 精河县| 甘南县| 黑龙江省| 新民市| 梁平县| 万山特区| 苏尼特左旗| 乌兰县| 来安县| 五家渠市| 南安市| 札达县| 周宁县| 惠州市| 新宾| 安多县| 顺昌县| 玛纳斯县| 正安县| 三门峡市| 黄浦区| 印江|