国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. ILDR2 Recombinant Monoclonal Antibody

ILDR2 Recombinant Monoclonal Antibody

  • 中文名稱：
    ILDR2 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA751251MA1HU
  • 規格：
    ￥1320
  • 圖片：
    • Immunofluorescence staining of Hela cell with CSB-RA751251MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).
    • Immunofluorescence staining of U251 cell with CSB-RA751251MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).
    • Overlay Peak curve showing Jurkat cells stained with CSB-RA751251MA1HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100.Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-human IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was human IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
  • 其他：

產品詳情

  • 產品描述：
    CSB-RA751251MA1HU ILDR2重組單克隆抗體是經ELISA、免疫熒光（IF）和流式細胞術（FC）嚴格驗證的高特異性科研工具。該抗體靶向ILDR2蛋白，該分子作為免疫球蛋白超家族成員，在細胞間連接復合體形成及上皮極性建立中發揮重要作用，與組織屏障功能調控密切相關。實驗數據顯示，該抗體在IF應用中能清晰呈現細胞膜或特定亞細胞結構的定位信號，推薦使用稀釋比例為1:50-1:200；在FC檢測中可有效識別天然構象的靶蛋白，推薦同等稀釋范圍。經ELISA驗證其具備優異的目標蛋白結合能力，適用于體外蛋白互作分析。本產品可廣泛應用于細胞連接機制研究、上皮組織發育模型構建，以及相關信號通路的功能解析等基礎研究領域，為探索ILDR2在細胞極性調控和生理病理過程中的分子機制提供可靠支持。
  • Uniprot No.：
  • 基因名：
  • 別名：
    ILDR2; C1orf32Immunoglobulin-like domain-containing receptor 2
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ILDR2 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    13G7
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
    FC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in lipid homeostasis and ER stress pathways.
  • 基因功能參考文獻：
    1. We demonstrated that ZNF70 interacts with ZFP64 and activates HES1 transcription by binding to the HES1 promoter. In addition, HES1 gene expression is increased in ILDR2-knockdown HepG2 cells, in which ZNF70 is translocated from the cytoplasm to the nucleus, suggesting that ZNF70 migration to the nucleus after dissociating from the ILDR2-ZNF70 complex activates HES1 transcription. These results support a novel link betwee PMID: 27353377
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19536175
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19064610
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, LISCH7 family
  • 數據庫鏈接：

    HGNC: 18131

    KEGG: hsa:387597

    UniGene: Hs.444835



主站蜘蛛池模板： 太仓市| 岐山县| 金华市| 江华| 当雄县| 平和县| 阿荣旗| 白朗县| 安塞县| 丽江市| 高淳县| 龙井市| 靖宇县| 墨江| 望江县| 深州市| 佛冈县| 苏州市| 新闻| 仪征市| 武胜县| 洛扎县| 库伦旗| 沾化县| 麻城市| 许昌县| 辰溪县| 太仓市| 磐石市| 安龙县| 鄂尔多斯市| 长兴县| 壶关县| 宁都县| 泗阳县| 上犹县| 延吉市| 卫辉市| 卢氏县| 双流县| 陕西省|