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  4. ACAA2 Recombinant Monoclonal Antibody

ACAA2 Recombinant Monoclonal Antibody

  • 中文名稱：
    ACAA2 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA568815A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of acetyl-CoA acyltransferase 2 expression in C2C12 cells using acetyl-CoA acyltransferase 2 antibody. Green, isotype control; red, acetyl-CoA acyltransferase 2.
    • Immunocytochemical staining of C2C12 cells with Acetyl-CoA acyltransferase 2 antibody. Nuclei were stained blue with DAPI; Acetyl-CoA acyltransferase 2 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar, 20 μm.
    • mmunohistochemistry was performed on paraffin-embedded human sigmoid colon carcinoma using acetyl-CoA acyltransferase 2 antibody. Antigen retrieval was done in sodium citrate buffer (pH 6.0). DAB was used for detection, with hematoxylin counterstaining. Images were acquired using a Nikon Ci-L Plus microscope (40× objective). Scale bar: 25 μm.
    • Western blotting analysis using acetyl-CoA acyltransferase 2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with acetyl-CoA acyltransferase 2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ACAA2
  • 別名：
    ACAA2; Acetyl-CoA Acyltransferase 2; DSAEC 2; Mitochondrial 3-Oxoacyl-Coenzyme A Thiolase 2; 3-Ketoacyl-CoA Thiolase, Mitochondrial; Mitochondrial 3-Oxoacyl-CoA Thiolase; Acetyl-Coenzyme A Acyltransferase 2; Acyl-CoA Hydrolase, Mitochondrial; Acetyl-CoA Acetyltransferase; EC 2.3.1.16; T1; Acetyl-CoA Acyltransferase; Beta Ketothiolase; Beta-Ketothiolase; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2; EC 2.3.1
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human ACAA2 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    14G6
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
    IHC 1:100-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation. Abolishes BNIP3-mediated apoptosis and mitochondrial damage.
  • 基因功能參考文獻：
    1. ACAA2 is a functional BNIP3 binding partner and provide a possible linkage between fatty acid metabolism and apoptosis of cells. PMID: 18371312
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Thiolase family
  • 數據庫鏈接：

    HGNC: 83

    OMIM: 604770

    KEGG: hsa:10449

    STRING: 9606.ENSP00000285093

    UniGene: Hs.200136



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