国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB5C Antibody

RAB5C Antibody

  • 中文名稱：
    RAB5C兔多克隆抗體
  • 貨號：
    CSB-PA040136
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    L1880 antibody; RAB; member of RAS oncogene family like antibody; RAB5C antibody; RAB5C; member of RAS oncogene family antibody; RAB5C; member RAS oncogene family antibody; RAB5C_HUMAN antibody; RAB5CL antibody; RAB5L antibody; RABL antibody; Ras-related protein Rab-5C antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Rab 5C.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Protein transport. Probably involved in vesicular traffic.
  • 基因功能參考文獻：
    1. We identify RAB5C as a new candidate gene for type-2 diabetes risk with a functional role in endosomal type-2 diabetes module. Functional analysis shows that RAB5C is tyrosine phosphorylated. Data analysis reveals a tyrosine phosphorylation motif in the GTP binding site of RAB5C which may be targeted by insulin receptor. Insulin-dependent tyrosine phosphorylation of RAB5C is inhibited by overexpression of HACD3 (PTPLAD1). PMID: 30300385
    2. Enforced miR-509 expression in NALM6 cells reduced RAB5C mRNA and protein levels, and RAB5C was demonstrated to be a direct target of miR-509. PMID: 25368993
    3. PLP2 and RAB5C are binding partners of TPD52. PMID: 24604726
    4. Rab5C modulates Rac1-mediated cell motility. PMID: 24587345
    5. GTP-Rab5c also bound to AMAP1, and activation of Rab5c by EGFR signaling was necessary to promote the intracellular association of AMAP1 and PRKD2 PMID: 22734003

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數據庫鏈接：

    HGNC: 9785

    OMIM: 604037

    KEGG: hsa:5878

    STRING: 9606.ENSP00000345689

    UniGene: Hs.650382



主站蜘蛛池模板： 南乐县| 威宁| 大竹县| 长白| 庄河市| 吉林省| 桓仁| 朝阳区| 中宁县| 南靖县| 进贤县| 潞城市| 修武县| 临沧市| 兴化市| 米泉市| 巴林左旗| 湾仔区| 磐安县| 大荔县| 宜宾市| 定陶县| 凉山| 凌海市| 永修县| 略阳县| 科尔| 米易县| 科技| 青浦区| 神池县| 抚州市| 南靖县| 绵竹市| 灌云县| 扎囊县| 天峨县| 武隆县| 老河口市| 乌拉特中旗| 新和县|