NENF Antibody, HRP conjugated

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NENF Polyclonal antibody
Uniprot No.：

Q9UMX5
基因名：

NENF
別名：

Cell growth inhibiting protein 47 antibody; Cell immortalization-related protein 2 antibody; CIR2 antibody; Nenf antibody; NENF_HUMAN antibody; Neudesin antibody; Neuron derived neurotrophic factor antibody; Neuron-derived neurotrophic factor antibody; SCIRP10 antibody; SCIRP10 related protein antibody; Secreted protein of unknown function antibody; Spinal cord injury related protein 10 antibody; SPUF antibody; SPUF protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Peptide sequence from Human Neudesin protein (149-167AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance.
基因功能參考文獻：
1. High NENF expression is associated with liver cancer. PMID: 24763612
2. Human neudesin of 172 amino acids with high similarity ( approximately 91% identity) to mouse neudesin was identified; the human neudesin gene was mapped to chromosome 1p33. PMID: 15605373
3. Describes the predicted heme-binding domains in the human neudesin protein sequence. PMID: 18056703
亞細胞定位：

Secreted, extracellular space. Mitochondrion. Endoplasmic reticulum.
蛋白家族：

Cytochrome b5 family, MAPR subfamily
組織特異性：

Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast.
數據庫鏈接：

HGNC: 30384

OMIM: 611874

KEGG: hsa:29937

STRING: 9606.ENSP00000355955

UniGene: Hs.461787