Western blot
All lanes: DNAJA2 antibody at 3.79μg/ml
Lane 1: A375 whole cell lysate
Lane 2: PC-3 whole cell lysate
Lane 3: HepG2 whole cell lysate
Lane 4: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
基因功能參考文獻:
we combined the Hsp70-NEF pairs with cochaperones of the J protein family (DnaJA1, DnaJA2, DnaJB1, and DnaJB4) to generate 16 permutations. PMID: 24318877
The DNAJA2 substrate release mechanism is essential for chaperone-mediated folding. PMID: 23091061
Hsp40 type 1 chaperones DJA1 (DNAJA1/Hdj2) and DJA2 (DNAJA2) as key modulators of hERG degradation PMID: 19940115
Rdj2 modulates G protein signaling and further suggest that chaperoning G proteins is an emerging theme of the J protein network. PMID: 18595009
Bag1 NEF increased refolding by Hsc70 and DJA2, as did the newly characterized NEF Hsp110 PMID: 18684711