DCAF6 Antibody

產品詳情

Uniprot No.：

Q58WW2
基因名：

DCAF6
別名：

1200006M05Rik antibody; Androgen receptor complex associated protein antibody; Androgen receptor complex-associated protein antibody; ARCAP antibody; DCAF6 antibody; DCAF6_HUMAN antibody; DDB1 and CUL4 associated factor 6 antibody; DDB1- and CUL4-associated factor 6 antibody; IQ motif and WD repeat-containing protein 1 antibody; IQ motif and WD repeats 1 antibody; IQWD1 antibody; MSTP055 antibody; NRIP antibody; Nuclear receptor interaction protein antibody; RP4 745I14.1 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human IQWD1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
基因功能參考文獻：
1. High IQWD1 expression is associated with breast cancer. PMID: 24222117
2. NRIP enhances HPV 16 gene expression via interaction with either GR or viral E2. PMID: 22177699
3. NRIP interacts with either androgen or glucocorticoid receptors PMID: 15784617
4. NRIP plays a feed-forward role enhancing androgen receptor (AR)-driven NRIP promoter activity via NRIP forming a complex with AR to protect AR protein from proteasome degradation. PMID: 17984071
5. A survey results showed that ten cancer cases were revealed to express the NRIP in six malignancies, but not all of these specific tumor types consistently showed positive NRIP expression. PMID: 18673574
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亞細胞定位：

Nucleus.
組織特異性：

Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland.
數據庫鏈接：

HGNC: 30002

OMIM: 610494

KEGG: hsa:55827

STRING: 9606.ENSP00000356814

UniGene: Hs.435741