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C8B Antibody

  • 中文名稱：
    C8B兔多克隆抗體
  • 貨號：
    CSB-PA004195ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: C8B antibody at 1.28µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Lane 3: Raji whole cell lysate
      Lane 4: Mouse liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 67 kDa
      Observed band size: 67 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA004195ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA004195ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) C8B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    C8b antibody; CO8B_HUMAN antibody; Complement component 8 beta polypeptide antibody; Complement component 8 subunit beta antibody; Complement component C8 beta chain antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Complement component C8 beta chain protein (55-350AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
  • 基因功能參考文獻：
    1. The binding specificity between C8 beta and C8 alpha subunits is determined by a cooperative interaction of the N-terminal thrombospondin type 1 module and the membrane attack complex/perforin domain. PMID: 12220191
    2. results indicate that the principal binding site for C9 lies within the MACPF domain of C8alpha; they also suggest this site and the binding sites for C8beta and C8gamma are distinct PMID: 16618117
  • 相關疾病：
    Complement component 8 deficiency, 2 (C8D2)
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Complement C6/C7/C8/C9 family
  • 數據庫鏈接：

    HGNC: 1353

    OMIM: 120960

    KEGG: hsa:732

    STRING: 9606.ENSP00000360281

    UniGene: Hs.391835



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