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ALDH4A1 Monoclonal Antibody

  • 中文名稱:
    ALDH4A1 Monoclonal Antibody
  • 貨號:
    CSB-MA068197
  • 規格:
    ¥1320
  • 圖片:
    • Western blotting analysis using ALDH4A1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with ALDH4A1 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他:

產品詳情

  • 產品名稱:
    Mouse anti-Homo sapiens (Human) ALDH4A1 Monoclonal antibody
  • Uniprot No.:
  • 基因名:
    ALDH4A1
  • 別名:
    ALDH4A1; Aldehyde Dehydrogenase 4 Family Member A1; L-Glutamate Gamma-Semialdehyde Dehydrogenase; P5CDh; ALDH4; Delta-1-Pyrroline-5-Carboxylate Dehydrogenase, Mitochondrial; Aldehyde Dehydrogenase Family 4 Member A1; P5C Dehydrogenase; Mitochondrial Delta-1-Pyrroline 5-Carboxylate Dehydrogenase; Delta-1-Pyrroline-5-Carboxylate Dehydrogenase; Aldehyde Dehydrogenase 4 Family, Member A1; Epididymis Secretory Sperm Binding Protein; EC 1.2.1.88; EC 1.5.1.12; P5CDH; P5CD
  • 宿主:
    Mouse
  • 反應種屬:
    Human, Rat
  • 免疫原:
    Recombinant Human ALDH4A1 protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    Mouse IgG1
  • 純化方式:
    Affinity-chromatography
  • 克隆號:
    13E11
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:2500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.
  • 基因功能參考文獻:
    1. the impact of the hyperprolinemia-associated mutation of Ser352 to Leu on the structure and catalytic properties of the P5CDH PMID: 22516612
    2. ALDH4 is a p53-inducible gene with a protective role in cellular stresses PMID: 14986171
    3. ALDH4 is transcriptionally induced by p53. PMID: 14986171
  • 相關疾病:
    Hyperprolinemia 2 (HYRPRO2)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Aldehyde dehydrogenase family
  • 組織特異性:
    Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.
  • 數據庫鏈接:

    HGNC: 406

    OMIM: 239510

    KEGG: hsa:8659

    STRING: 9606.ENSP00000290597

    UniGene: Hs.77448