Mouse anti-double stranded DNA antibody (IgG) ELISA Kit

文獻(xiàn)引用 (28) 評價 (3) 說明書下載

中文名稱：

小鼠抗雙鏈DNA抗體/天然DNA抗體(IgG)酶聯(lián)免疫試劑盒
貨號：

CSB-E11194m
規(guī)格：

96T/48T
價格：

￥3200/￥2500
促銷：
其他：

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產(chǎn)品描述：

小鼠抗雙鏈DNA抗體/天然DNA抗體(IgG)酶聯(lián)免疫試劑盒（CSB-E11194m）為間接法 ELISA試劑盒，定性檢測血清樣本中的dsDNA Ab (IgG)含量。dsDNA Ab (IgG)即抗雙鏈DNA抗體（IgG型）。它是系統(tǒng)性紅斑狼瘡（SLE）的重要血清學(xué)標(biāo)志物，與疾病的發(fā)生發(fā)展密切相關(guān)。其研究機(jī)制主要是它能與雙鏈DNA結(jié)合形成免疫復(fù)合物，沉積在組織器官，激活補(bǔ)體系統(tǒng)，進(jìn)而引發(fā)炎癥反應(yīng)損傷組織。本產(chǎn)品適用于科研實驗中評估小鼠自身免疫疾病模型（如系統(tǒng)性紅斑狼瘡）的抗體動態(tài)變化、病理機(jī)制研究或藥物干預(yù)效果分析，為探索抗dsDNA抗體在免疫異常反應(yīng)中的作用提供實驗支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
縮寫：

dsDNA Ab (IgG)
種屬：

Mus musculus (Mouse)
樣本類型：

serum
檢測范圍：
靈敏度：
反應(yīng)時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Others
測定原理：

qualitative
測定方法：

Indirect
標(biāo)準(zhǔn)曲線：
貨期：

3-5 working days

引用文獻(xiàn)

Inhibition of long-lived plasma cells, a critical role for Telitacicept treatment to systemic lupus erythematosus E Zhang, C Zhao, F Wang, L Wang, S Li,Immunopharmacology and Immunotoxicology,2025
Exposure to Dietary Nitrite Exacerbates Lupus in MRL/lpr Mice by Enhancing Integrin Alpha M Y Qiu, Q Zhang, X Yang, C Wen, Z He, M Wang,Inflammation,2025
Genetically engineered extracellular vesicles expressing decoy protein TACI provide a therapeutic effect in systemic lupus erythematosus mouse model M Cai, F Tian, J Han, L Wang, S Hu, P Dong,Journal of Controlled Release,2025
Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration L Gao, Y Zhang, Z Hu, S Chen, Q Wang,Advanced Science,2025
Ginsenoside CK potentiates SIRT1 to alleviate lupus nephritis through compensating for XBP1-mediated endoplasmic reticulum stress in plasma cells Z Song, Y Li, S Xu, S Qian, W Xu, L Xu, F Tian,Journal of Pharmaceutical Analysis,2025
MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway P Huang, G Yang, P Zhang, Y Zhu, Y Guan, J Sun,Cell Death & Disease,2025
Dysregulation in keratinocytes drives systemic lupus erythematosus onset J Tian, L Shi, D Zhang, X Yao, M Zhao,Cellular & Molecular Immunology,2025
SATB1 prevents immune cell infiltration by regulating chromatin organization and gene expression of a chemokine gene cluster in T cells B Wang, Q Bian,Communications Biology,2024
TM9SF1 expression correlates with autoimmune disease activity and regulates antibody production through mTOR-dependent autophagy J Xiao, Z Zhao, F Zhou, J Xiong, Z Yang,BMC medicine,2024
A rationally designed CD19 monoclonal antibody-triptolide conjugate for the treatment of systemic lupus erythematosus L Wang, H Yin, J Jiang, Q Li, C Gao, W Li,Acta Pharmaceutica Sinica B,2024
MME and PTPRC: key renal biomarkers in lupus nephritis M Wen, M Hun, M Zhao, Q He,PeerJ,2024
Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumonia aggravation L Pan,Cell Death Discovery,2024
Mesenchymal stem cells-derived extracellular vesicles ameliorate lupus nephritis by regulating T and B cell responses C Li,Stem cell research & therapy,2024
Jieduquyuziyin prescription attenuates the side effect of prednisone through regulating gut microbiota when in the combination with prednisone treat MRL/lpr mice Z Zhu,Journal of Traditional and Complementary Medicine,2024
Deletion of the Mitochondrial Membrane Protein Fam210b Is Associated with the Development of Systemic Lupus Erythematosus Y Xu,International Journal of Molecular Sciences,2024
Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses B Qian,Cell reports,2024
Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice H Chen,The Science of the total environment,2023
The phagocytosis dysfunction in lupus nephritis is related to monocyte/macrophage CPT1a Q Yuan,Immunology letters,2024
Endogenous retrovirus promotes the aberrant T cell differentiation in systemic lupus erythematosus via RIG-I pathway R Patil,/,2024
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation J Zhao,Journal of autoimmunity,2023
Blockade of OX40/OX40L signaling using anti-OX40L delays disease progression in murine lupus J Zhao,researchsquare,2023
Gut microbiota mediated the effects of high relative humidity on lupus in female MRL/lpr mice C Wang,Advances in rheumatology,2023
LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus L Liu,Clinical and translational medicine,2022
Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling. X Wang,Mediators of Inflammation,2022
GDF-15: A Potential Biomarker and Therapeutic Target in Systemic Lupus Erythematosus WD Xu,Frontiers in immunology,2022
Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B cell activation to ameliorate systemic lupus erythematosus L Sheng,International Journal of Molecular Medicine,2020
MicroRNA-10a-3p mediates Th17/Treg cell balance and improves renal injury by inhibiting REG3A in lupus nephritis G You,International Immunopharmacology,2020
Interleukin-25 is upregulated in patients with systemic lupus erythematosus and ameliorates murine lupus by inhibiting inflammatory cytokine production Li Y,International Immunopharmacology,2019

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產(chǎn)品評價

平均分:

5.0分 - 3 個評價

樣品類型：血漿（抗凝劑）

樣品信息：小鼠

稀釋比：其他

產(chǎn)品評價：我用CSB-E11194m檢測正常及SLE模型小鼠血漿中IgG的表達(dá)情況，1:10稀釋后其OD值在0.19~0.649之間，測量的結(jié)果濃度較低。產(chǎn)品操作便捷，使用方便，說明書詳細(xì)，但建議不同樣本要進(jìn)行預(yù)實驗摸好濃度范圍再進(jìn)行大批量實驗。

By 楊老師

樣品類型：血清

樣品信息：小鼠

稀釋比：其他 1:10

產(chǎn)品評價：我用CSB-E11194m試劑盒檢測了小鼠的dsDNA

By 邱老師

樣品類型：血漿（抗凝劑）稀釋20倍

樣品信息：小鼠

稀釋比：其他 1:20

產(chǎn)品評價：我用CSB-11194m檢測小鼠血漿的自身抗體，這個elisa試劑盒的效果十分穩(wěn)定，周圍人也全是用的華美的試劑盒。以前用過其他家的試劑盒，感覺都不如華美可靠，以后會繼續(xù)使用，給我們科研很大的便利。合作愉快。

By 王老師

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Mouse anti-double stranded DNA antibody (IgG) ELISA Kit

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