tst
TST,即硫氧還蛋白相互作用蛋白(也常被叫做TXNIP或VDUP1)是一種與細(xì)胞內(nèi)氧化狀態(tài)調(diào)節(jié)相關(guān)的蛋白。它能和硫氧還蛋白結(jié)合,改變后者的活性,進(jìn)而影響細(xì)胞應(yīng)對氧化壓力的能力。在日常代謝過程中,這種蛋白的表達(dá)水平會隨血糖變化波動,和葡萄糖的利用關(guān)系密切——當(dāng)血糖升高時,它的含量往往上升,可能干擾胰島素的正常作用。
TST和多種疾病存在關(guān)聯(lián):比如2型糖尿病患者體內(nèi),它的水平常出現(xiàn)異常,可能加重胰島素抵抗的情況;部分腫瘤中,它的表達(dá)變化也被觀察到,與細(xì)胞過度增殖或凋亡失衡有關(guān)。目前針對它的藥物研究還處于早期階段,一些實(shí)驗(yàn)室正在嘗試開發(fā)能調(diào)節(jié)其功能的小分子物質(zhì),希望用于改善代謝紊亂或抑制腫瘤生長。
熱銷產(chǎn)品
TST Antibody (CSB-PA620980LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Rat liver tissue
All lanes: TST antibody at 5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 34 kDa
Observed band size: 34 kDa
IHC image of CSB-PA620980LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA620980LA01HU diluted at 1:400 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Human Thiosulfate sulfurtransferase(TST) ELISA kit (CSB-EL025197HU)
驗(yàn)證數(shù)據(jù)
貨號:CSB-EL025197HU
規(guī)格:96T/48T
靈敏度:3.9 pg/mL
檢測范圍:15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
tst Antibodies
tst for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA025197GA01HU | TST Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA620980LA01HU | TST Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA620980LB01HU | TST Antibody, HRP conjugated | Human | ELISA |
| CSB-PA620980LC01HU | TST Antibody, FITC conjugated | Human | |
| CSB-PA620980LD01HU | TST Antibody, Biotin conjugated | Human | ELISA |
tst Proteins
tst Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP620980HU CSB-EP620980HU CSB-BP620980HU CSB-MP620980HU CSB-EP620980HU-B |
Recombinant Human Thiosulfate sulfurtransferase (TST) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
tst ELISA Kit
tst ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL025197HU | Human Thiosulfate sulfurtransferase(TST) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 3.9 pg/mL |






