国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

XPO1

XPO1,即染色體區域維持1蛋白(Chromosome Region Maintenance 1 Protein),也被稱為出口蛋白1(Exportin 1),是一種在細胞核輸出過程中發揮關鍵作用的蛋白質。它通過識別并結合含有核輸出信號的貨物,如某些RNA和蛋白質,將它們從細胞核運輸到細胞質中。XPO1的來源是細胞自身的基因編碼,它在細胞分裂、基因表達調控、細胞信號傳遞等方面發揮著重要作用。其作用機制涉及到與Ran GTPase蛋白的相互作用,以及與貨物蛋白的結合和釋放,從而實現物質的定向運輸。XPO1在生物學上的意義非常廣泛,它涉及到細胞內多種信號通路的調控,包括但不限于p53信號通路、NF-κB信號通路等,這些信號通路與細胞的生長、分化、凋亡以及對外界刺激的響應密切相關。XPO1的功能異常與多種疾病相關,特別是在癌癥中,XPO1的過表達與腫瘤的侵襲性、轉移和化療抵抗性有關。因此,XPO1成為了抗癌藥物開發的重要靶點,通過抑制XPO1的活性,可以阻止腫瘤相關蛋白的核輸出,進而影響腫瘤細胞的生長和存活。

熱銷產品

XPO1 Recombinant Monoclonal Antibody (CSB-RA930964A0HU)

驗證數據

CSB-RA930964A0HU

IHC image of CSB-RA930964A0HU diluted at 1:100 and staining in paraffin-embedded human ovarian tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA930964A0HU

IHC image of CSB-RA930964A0HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

XPO1 Antibodies

XPO1 for Homo sapiens (Human)

XPO1 Proteins

XPO1 Proteins for Homo sapiens (Human)

XPO1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

XPO1 Proteins for Dictyostelium discoideum (Slime mold)

XPO1 Proteins for Mus musculus (Mouse)

XPO1 Proteins for Rattus norvegicus (Rat)



主站蜘蛛池模板: 大城县| 横峰县| 丘北县| 衡东县| 天祝| 义乌市| 毕节市| 大渡口区| 扎兰屯市| 固原市| 资源县| 荆州市| 岳阳市| 梁河县| 宕昌县| 新蔡县| 丰镇市| 江达县| 吴忠市| 临澧县| 开化县| 鄂尔多斯市| 米林县| 上虞市| 蛟河市| 长兴县| 文水县| 营口市| 伊吾县| 勃利县| 昭苏县| 雷山县| 周宁县| 巴南区| 南漳县| 红安县| 尉氏县| 大石桥市| 石城县| 元谋县| 资兴市|