TYMS

TYMS（胸苷酸合成酶）是DNA合成過程中的關(guān)鍵酶，由兩個相同亞單位組成的二聚體蛋白，位于第18號染色體上。其主要功能是將脫氧尿嘧啶核苷酸（dUMP）與五氫葉酸（FH4）催化成脫氧胸腺嘧啶核苷酸（dTMP），這一反應(yīng)對于細胞DNA復(fù)制和修復(fù)至關(guān)重要。TYMS在細胞生長和增殖中起到核心作用，其表達水平在腫瘤細胞中通常較高，與腫瘤細胞的增殖、浸潤和轉(zhuǎn)移密切相關(guān)。因此，TYMS成為抗腫瘤藥物的重要靶點，如5-氟尿嘧啶（5-FU）等化療藥物通過抑制TYMS活性來阻止DNA合成，從而抑制腫瘤細胞生長。TYMS的研究不僅有助于理解細胞生物學(xué)過程，還為抗腫瘤藥物的研發(fā)提供了新途徑。

熱銷產(chǎn)品

TYMS Recombinant Monoclonal Antibody (CSB-RA584889A0HU)

驗證數(shù)據(jù)

Western Blot
Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HepG2 whole cell lysate, HL-60 whole cell lysate
All lanes: Thymidylate Synthase antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 36, 32, 27 kDa
Observed band size: 36 kDa

TYMS Antibody

TYMS Protein

TYMS ELISA Kit

TYMS Antibodies

TYMS for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA025393GA01HU	TYMS Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA025393LA01HU	TYMS Antibody	Human	ELISA, WB, IF, IP
CSB-PA025393LB01HU	TYMS Antibody, HRP conjugated	Human	ELISA
CSB-PA025393LC01HU	TYMS Antibody, FITC conjugated	Human
CSB-PA025393LD01HU	TYMS Antibody, Biotin conjugated	Human	ELISA
CSB-RA584889A0HU	TYMS Recombinant Monoclonal Antibody	Human	ELISA, WB

TYMS Proteins

TYMS Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP025393HU CSB-EP025393HU CSB-BP025393HU CSB-MP025393HU CSB-EP025393HU-B	Recombinant Human Thymidylate synthase (TYMS)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli