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TRPM7

Transient receptor potential cation channel subfamily M member 7 is a protein in humans that is encoded by TRPM7 gene. Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

TRPM7 Antibodies

TRPM7 for Homo sapiens (Human)

TRPM7 Proteins

TRPM7 Proteins for Rattus norvegicus (Rat)

TRPM7 Proteins for Mus musculus (Mouse)

TRPM7 Proteins for Homo sapiens (Human)