TPH2

TPH2，常被稱作腦型色氨酸羥化酶，是體內合成5-羥色胺的關鍵分子之一，主要分布在大腦與脊髓的神經細胞中。它能將色氨酸轉化為5-羥色氨酸，這是生成5-羥色胺的起始步驟，而5-羥色胺對情緒、睡眠、食欲等多種生理功能的調節至關重要。TPH2活性異常，可能影響5-羥色胺水平，進而與抑郁癥、焦慮癥、雙相情感障礙等精神類疾病關聯緊密，部分研究也提示它與睡眠障礙、帕金森病等神經問題存在聯系。藥物研發領域，一些候選藥物正針對它展開探索，通過調控其活性來調整中樞5-羥色胺含量，嘗試用于抑郁癥等疾病治療，但多數仍處于臨床試驗階段，尚未普及到臨床應用。

熱銷產品

Recombinant Human Tryptophan 5-hydroxylase 2 (TPH2) (CSB-CF809000HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TPH2 Antibody (CSB-PA809000LA01HU)

驗證數據

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA809000LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA809000LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA809000LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Western Blot
Positive WB detected in: Rat heart tissue, Mouse stomach tissue
All lanes: TPH2 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 57 kDa
Observed band size: 57 kDa

TPH2 Antibody

TPH2 Protein

TPH2 Antibodies

TPH2 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA123981	Phospho-TPH2 (Ser19) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA272667	TPH2 (Ab-19) Antibody	Human,Mouse	ELISA,WB
CSB-PA006958	Phospho-TPH2 (S19) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA006960	TPH2 Antibody	Human,Mouse,Rat,Monkey	WB, ELISA
CSB-PA161937	TPH2 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA917997	TPH2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA809000LA01HU	TPH2 Antibody	Human, Mouse, Rat	ELISA, WB, IHC, IF
CSB-PA809000LC01HU	TPH2 Antibody, FITC conjugated	Human

TPH2 Proteins

TPH2 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP809000HU CSB-BP809000HU CSB-EP809000HU-B	Recombinant Human Tryptophan 5-hydroxylase 2 (TPH2)	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP809000HU	Recombinant Human Tryptophan 5-hydroxylase 2 (TPH2)	E.coli