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TMEFF2

TMEFF2(Transmembrane Protein with EGF-like and Two Follistatin-like domains 2)是一種跨膜蛋白,在人類組織中廣泛表達。其結構包括一個信號肽、一個EGF樣結構域和兩個Follistatin樣結構域。TMEFF2在多種生理和病理過程中發揮重要作用,包括胚胎發育、神經發育、神經保護和腫瘤發生等。

研究表明,TMEFF2在多種癌癥中具有不同的作用。例如,在乳腺癌、前列腺癌和肺癌等多種腫瘤中,TMEFF2的表達水平明顯降低,與腫瘤發生和進展密切相關。另外,一些研究表明TMEFF2可能具有抗腫瘤的作用,例如在胃癌中表達TMEFF2的患者存活期更長。因此,TMEFF2被認為是一個重要的癌癥治療靶點,對其研究和開發相關藥物具有重要意義。

更多TMEFF2相關閱讀:表皮生長因子TMEFF2:腫瘤特異性或甲基化標志物,雙功能靶點蘊藏新機會!

熱銷產品

Recombinant Human TMEFF2, partial (Active) CSB-MP883439HU

驗證數據

High Purity Validated by SDS-PAGE

The purity was greater than 95% as determined by SDS-PAGE.

Excellent Bioactivity Validated by Functional ELISA

Immobilized Human TMEFF2 at 2 μg/mL can bind Anti-TMEFF2 recombinant antibody (CSB-RA883439MA1HU), the EC50 is 2.129-2.956 ng/mL.

Recombinant Macaca fascicularis Jacalin-type lectin domain-containing protein (Active) CSB-MP4727MOV

驗證數據

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ZG16B at 2μg/mL can bind Anti-ZG16B recombinant antibody (CSB-RA836195MA1HU), the EC50 is 20.15-28.98 ng/mL.

TMEFF2 Antibodies

TMEFF2 for Homo sapiens (Human)

TMEFF2 Proteins

TMEFF2 Proteins for Bos taurus (Bovine)

TMEFF2 Proteins for Pongo abelii (Sumatran orangutan)

TMEFF2 Proteins for Homo sapiens (Human)

TMEFF2 Proteins for Mus musculus (Mouse)



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