TDO2
TDO2，即色氨酸2,3-雙加氧酶，別名TO、TDO、TPH2、TRPO、HYPTRP。TDO2由人類TDO2基因編碼，該基因位于4號染色體的q32.1區(qū)域。TDO2是一種血紅素酶，在色氨酸代謝中發(fā)揮關(guān)鍵作用，通過催化犬尿氨酸途徑的第一步和限速步驟，將色氨酸轉(zhuǎn)化為犬尿氨酸。TDO2的活性增加和隨后犬尿氨酸的產(chǎn)生可能通過抑制抗腫瘤免疫反應(yīng)在癌癥中發(fā)揮作用，且該基因中的單核苷酸多態(tài)性可能與自閉癥有關(guān)。TDO2在調(diào)節(jié)全身的色氨酸水平中起關(guān)鍵作用，并在癌癥免疫學(xué)中具有重要作用。
熱銷產(chǎn)品
Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) (CSB-EP023351HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TDO2 Proteins
TDO2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023351HU | Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) | Yeast |
| CSB-EP023351HU | Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) | E.coli |
| CSB-BP023351HU CSB-MP023351HU CSB-EP023351HU-B |
Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023351HUb2 | Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) | E.coli |
