STC1

STC1，全名為Stanniocalcin-1，別名STC，是一種分泌型同型二聚體糖蛋白，在多種組織中表達(dá)，可能具有自分泌或旁分泌功能。該蛋白在腎臟和腸道鈣和磷酸鹽轉(zhuǎn)運(yùn)、細(xì)胞代謝或細(xì)胞鈣/磷酸鹽穩(wěn)態(tài)的調(diào)節(jié)中發(fā)揮作用。研究表明，STC1蛋白的表達(dá)與乳腺癌的轉(zhuǎn)移、化療抵抗等病理參數(shù)相關(guān)性。在炎癥性腸病（如克羅恩病）中，STC1蛋白表達(dá)顯著增加，并在氧化應(yīng)激誘導(dǎo)的細(xì)胞死亡和炎癥反應(yīng)中起關(guān)鍵作用。此外，STC1蛋白還與肝細(xì)胞癌、卵巢癌和乳腺癌的發(fā)生發(fā)展相關(guān)。目前，針對STC1蛋白的藥物研發(fā)尚處于探索階段，但已有研究表明，抑制STC1蛋白的表達(dá)或活性可能成為治療這些疾病的新策略。

熱銷產(chǎn)品

Recombinant Human Stanniocalcin-1 (STC1), partial (CSB-EP022821HU1)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

STC1 Antibody (CSB-PA022821ESR1HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA022821ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA022821ESR1HU at dilution of 1:100

STC1 Antibody

STC1 Protein

STC1 ELISA Kit

STC1 Antibodies

STC1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA022821GA01HU	STC1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA022821ESR1HU	STC1 Antibody	Human	ELISA, IHC
CSB-PA631492	STC1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA09889A0Rb	STC1 Antibody	Human	ELISA, IHC
CSB-PA09889C0Rb	STC1 Antibody, FITC conjugated	Human
CSB-PA09889B0Rb	STC1 Antibody, HRP conjugated	Human	ELISA

STC1 Proteins

STC1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP022821HU CSB-EP022821HU CSB-BP022821HU CSB-MP022821HU CSB-EP022821HU-B	Recombinant Human Stanniocalcin-1 (STC1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP022821HU1	Recombinant Human Stanniocalcin-1 (STC1), partial	E.coli
CSB-EP022821HU1a2	Recombinant Human Stanniocalcin-1 (STC1), partial	E.coli