SRSF10
SRSF10，即富含絲氨酸/精氨酸的剪接因子10。別名FUSIP1、FUSIP2、NSSR、SFRS13、SFRS13A、SRp38、SRrp40、TASR、TASR1、TASR2。SRSF10是哺乳動(dòng)物剪接調(diào)節(jié)因子家族的成員，稱為SR蛋白，由RNA結(jié)合域（RRM）和富含精氨酸和絲氨酸的輔助域（RS）組成，這些結(jié)構(gòu)域指導(dǎo)與其他蛋白質(zhì)的相互作用。SRSF10的作用機(jī)制涉及通過磷酸化狀態(tài)的變化來(lái)調(diào)控其活性，這一狀態(tài)在有絲分裂、熱休克和DNA損傷期間會(huì)發(fā)生變化。SRSF10通過控制特定轉(zhuǎn)錄本的選擇性剪接，影響葡萄糖、脂肪和膽固醇代謝、胚胎心臟的發(fā)育以及神經(jīng)過程。SRSF10對(duì)于HIV-1和其他病毒轉(zhuǎn)錄物的正確表達(dá)和加工也很重要。SRSF10在應(yīng)激反應(yīng)、器官發(fā)育和病毒復(fù)制中發(fā)揮關(guān)鍵作用，是對(duì)抗癌癥和病毒感染的潛在治療靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Serine/arginine-rich splicing factor 10 (SRSF10) (CSB-EP525638HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP525638HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) SRSF10.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP525638HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) SRSF10.
SRSF10 Antibody (CSB-PA525638LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA525638LA01HU at dilution of 1:100
SRSF10 Antibodies
SRSF10 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA525638LA01HU | SRSF10 Antibody | Human | ELISA, IHC |
SRSF10 Proteins
SRSF10 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP525638HU CSB-BP525638HU CSB-MP525638HU CSB-EP525638HU-B |
Recombinant Human Serine/arginine-rich splicing factor 10 (SRSF10) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP525638HU | Recombinant Human Serine/arginine-rich splicing factor 10 (SRSF10) | E.coli |
