SPIN1
SPIN1，全稱Spinster homolog 1 (Drosophila)，是一種參與細(xì)胞進(jìn)程的重要蛋白。該蛋白常見(jiàn)別名包括紡錘體蛋白1，在細(xì)胞分裂和基因表達(dá)調(diào)控中發(fā)揮關(guān)鍵作用。SPIN1蛋白通過(guò)與其他蛋白相互作用，影響細(xì)胞周期調(diào)控和染色質(zhì)結(jié)構(gòu)。研究表明，SPIN1蛋白與多種疾病相關(guān)，包括非小細(xì)胞肺癌和顱內(nèi) cavernous angioma。在藥物研發(fā)方面，針對(duì)SPIN1蛋白的抑制劑被探索用于治療癌癥，例如通過(guò)抑制其表達(dá)來(lái)阻斷腫瘤生長(zhǎng)。此外，SPIN1蛋白還在帕金森癥等神經(jīng)退行性疾病中發(fā)揮作用，為相關(guān)藥物篩選提供了新靶點(diǎn)。目前，針對(duì)SPIN1蛋白的抗體和重組蛋白產(chǎn)品已廣泛應(yīng)用于科研和臨床檢測(cè)，為疾病研究和治療提供了重要工具。
熱銷產(chǎn)品
Recombinant Human Spindlin-1 (SPIN1) (CSB-EP897305HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SPIN1 Antibody (CSB-PA897305DSR1HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: SPIN1 antibody at 1.45µg/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Lane 3: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 30 kDa
Observed band size: 30 kDa
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA897305DSR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA897305DSR1HU at dilution of 1:100
SPIN1 Antibodies
SPIN1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA022570GA01HU | SPIN1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA548594 | SPIN1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004138 | SPIN1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA897305DSR1HU | SPIN1 Antibody | Human | ELISA, WB, IHC |
SPIN1 Proteins
SPIN1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP897305HU CSB-BP897305HU CSB-MP897305HU CSB-EP897305HU-B |
Recombinant Human Spindlin-1 (SPIN1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP897305HU | Recombinant Human Spindlin-1 (SPIN1) | E.coli |
