国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

SMURF2

E3 ubiquitin-protein ligase SMURF2 is a protein in humans that is encoded by SMURF2 gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3. In this way, SMAD2 may recruit substrates, such as SNON, for ubiquitin-mediated degradation. Enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2.

SMURF2 Antibodies

SMURF2 for Homo sapiens (Human)

SMURF2 Proteins

SMURF2 Proteins for Mus musculus (Mouse)

SMURF2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

SMURF2 Proteins for Xenopus laevis (African clawed frog)

SMURF2 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 安吉县| 甘孜县| 芜湖市| 辽中县| 鄂州市| 宣汉县| 咸宁市| 利辛县| 象山县| 汉源县| 确山县| 古交市| 阿城市| 胶南市| 阳朔县| 拜城县| 河南省| 仁布县| 壤塘县| 杂多县| 铁岭市| 松阳县| 秭归县| 隆德县| 瑞丽市| 安国市| 蕲春县| 泸州市| 石台县| 建阳市| 陕西省| 达日县| 沙河市| 偃师市| 云霄县| 赣榆县| 宕昌县| 靖宇县| 卫辉市| 长乐市| 九江市|