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SLC27A2

Very long-chain acyl-CoA synthetase is a protein in humans that is encoded by SLC27A2 gene. Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precursors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).

SLC27A2 Antibodies

SLC27A2 for Homo sapiens (Human)

SLC27A2 Proteins

SLC27A2 Proteins for Rattus norvegicus (Rat)

SLC27A2 Proteins for Mus musculus (Mouse)

SLC27A2 Proteins for Homo sapiens (Human)