SLC25A10
SLC25A10，全稱溶質(zhì)載體家族25成員10，是一種參與二羧酸轉(zhuǎn)運(yùn)的蛋白質(zhì)。它能夠?qū)⑻O果酸、琥珀酸等二羧酸從線粒體基質(zhì)轉(zhuǎn)運(yùn)到胞質(zhì)，從而參與三羧酸循環(huán)、脂肪酸合成和糖異生等重要代謝過(guò)程。SLC25A10的常見(jiàn)別名包括DIC和MTDPS19。研究表明，SLC25A10在骨肉瘤組織中高表達(dá)，并且與患者的不良預(yù)后密切相關(guān)。此外，STUB1蛋白能夠調(diào)控SLC25A10的表達(dá)，進(jìn)而影響骨肉瘤細(xì)胞的增殖和遷移。因此，SLC25A10和STUB1被認(rèn)為是骨肉瘤治療的潛在靶點(diǎn)。在藥物研發(fā)方面，針對(duì)SLC25A10的靶向治療藥物正在開(kāi)發(fā)中，有望為骨肉瘤患者帶來(lái)新的治療選擇。
熱銷產(chǎn)品
SLC25A10 Antibody (CSB-PA883371LA01HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: SLC25A10 antibody at 16µg/ml
Lane 1: Mouse liver tissue
Lane 2: Mouse kidney tissue
Lane 3: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 32, 33 kDa
Observed band size: 32, 24 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA883371LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostata cancer using CSB-PA883371LA01HU at dilution of 1:100
SLC25A10 Antibodies
SLC25A10 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA021476GA01HU | SLC25A10 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA883371LA01HU | SLC25A10 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA883371LB01HU | SLC25A10 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA883371LC01HU | SLC25A10 Antibody, FITC conjugated | Human | |
| CSB-PA883371LD01HU | SLC25A10 Antibody, Biotin conjugated | Human | ELISA |
SLC25A10 Proteins
SLC25A10 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP883371HU1 CSB-EP883371HU1 CSB-BP883371HU1 CSB-MP883371HU1 CSB-EP883371HU1-B |
Recombinant Human Mitochondrial dicarboxylate carrier (SLC25A10), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF883371HU | Recombinant Human Mitochondrial dicarboxylate carrier (SLC25A10) | in vitro E.coli expression system |
