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SLC16A11

SLC16A11,即溶質載體家族16成員11,別名MCT11。SLC16A11是一種單羧酸轉運蛋白,負責丙酮酸的跨膜轉運,參與脂質代謝過程,并位于內質網膜和質膜上。SLC16A11通過質子耦聯機制轉運單羧酸類物質,包括丙酮酸、乳酸、酮體和短鏈脂肪酸,其轉運方向由細胞膜兩側的質子和單羧酸鹽濃度梯度決定。SLC16A11的功能異常與多種疾病相關,如2型糖尿病、胰島素抵抗和血脂代謝異常。SLC16A11在肝臟中表達,其變異可能通過影響肝臟細胞的乳酸轉運和甘油三酯代謝功能,進而影響糖尿病的發生和發展。

熱銷產品

SLC16A11 Antibody (CSB-PA843323LA01HU)

驗證數據

CSB-PA843323LA01HU

Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate
All lanes: SLC16A11 antibody at 3.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa

CSB-PA843323LA01HU

Immunofluorescence staining of A549 cells with CSB-PA843323LA01HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

SLC16A11 Antibodies

SLC16A11 for Homo sapiens (Human)

SLC16A11 Proteins

SLC16A11 Proteins for Homo sapiens (Human)