SERPINE1

SERPINE1，即絲氨酸蛋白酶抑制劑家族E成員1，別名PAI-1、PLANH1，是一種由人體基因SERPINE1編碼的分泌型糖蛋白，屬于絲氨酸蛋白酶抑制劑超家族中的一員，主要在血管內(nèi)皮細(xì)胞中產(chǎn)生，但也可在其他組織如脂肪組織中分泌。
SERPINE1通過抑制尿激酶和組織型纖溶酶原激活劑（uPA和tPA）的活性，從而調(diào)節(jié)凝血與纖溶系統(tǒng)。
SERPINE1參與多種生理和病理過程，包括纖維蛋白溶解、纖維化、血管生成、傷口愈合以及腫瘤細(xì)胞的侵襲和轉(zhuǎn)移。異常的SERPINE1表達(dá)與多種疾病相關(guān)，如代謝綜合征、哮喘、重度抑郁癥以及衰老相關(guān)疾病，且與血栓形成傾向有關(guān)。

熱銷產(chǎn)品

Recombinant Human Plasminogen activator inhibitor 1 (SERPINE1), partial (CSB-EP021081HU1e0)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SERPINE1 Recombinant Monoclonal Antibody (CSB-RA156066A0HU)

驗(yàn)證數(shù)據(jù)

Western Blot
Positive WB detected in: U-251 whole cell lysate, U-87 whole cell lysate
All lanes: PAI1 Antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46, 44 kDa
Observed band size: 45 kDa

IHC image of CSB-RA156066A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

SERPINE1 Antibody

SERPINE1 Protein

SERPINE1 ELISA Kit

SERPINE1 Antibodies

SERPINE1 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA11239A0Rb	SERPINE1 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA021081GA01HU	SERPINE1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA11239B0Rb	SERPINE1 Antibody, HRP conjugated	Human	ELISA
CSB-PA003699	SERPINE1 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA122189	SERPINE1 Antibody	Human,Rat	ELISA,IHC
CSB-RA156066A0HU	SERPINE1 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

SERPINE1 Proteins

SERPINE1 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP021081PI CSB-EP021081PI CSB-BP021081PI CSB-MP021081PI CSB-EP021081PI-B	Recombinant Pig Plasminogen activator inhibitor 1 (SERPINE1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SERPINE1 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP021081BO CSB-EP021081BO CSB-BP021081BO CSB-MP021081BO CSB-EP021081BO-B	Recombinant Bovine Plasminogen activator inhibitor 1 (SERPINE1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SERPINE1 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP021081MO	Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)	Yeast
CSB-EP021081MO	Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)	E.coli
CSB-BP021081MO CSB-MP021081MO CSB-EP021081MO-B	Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SERPINE1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP021081HU CSB-EP021081HU CSB-BP021081HU CSB-MP021081HU CSB-EP021081HU-B	Recombinant Human Plasminogen activator inhibitor 1 (SERPINE1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP021081HU1	Recombinant Human Plasminogen activator inhibitor 1 (SERPINE1), partial	E.coli
CSB-EP021081HU1e0	Recombinant Human Plasminogen activator inhibitor 1 (SERPINE1), partial	E.coli

SERPINE1 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP021081RA CSB-BP021081RA CSB-MP021081RA CSB-EP021081RA-B	Recombinant Rat Plasminogen activator inhibitor 1 (Serpine1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP021081RA	Recombinant Rat Plasminogen activator inhibitor 1 (Serpine1)	E.coli

SERPINE1 Proteins for Mustela vison (American mink) (Neovison vison)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP021081MVE CSB-EP021081MVE CSB-BP021081MVE CSB-MP021081MVE CSB-EP021081MVE-B	Recombinant Mustela vison Plasminogen activator inhibitor 1 (SERPINE1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli