RIOK2
RIOK2,全稱為RIO激酶2,常見別名包括RIK2。它在細胞內參與蛋白質合成的關鍵環節,同時也會影響細胞生長與分裂的節奏。臨床研究顯示,RIOK2異常表達或活性變化與多種癌癥相關——急性髓系白血病患者體內常能檢測到它的水平升高,這可能推動癌細胞不受控制地增殖;非小細胞肺癌中,它也被視作促進腫瘤進展的因素之一。針對RIOK2的藥物研發尚處早期階段,科研人員正探索抑制其功能的小分子化合物,希望借此阻斷腫瘤細胞的生長信號,但這些候選藥物仍需更多臨床試驗驗證。
熱銷產品
RIOK2 Antibody (CSB-PA887136LA01HU)
驗證數據
IHC image of CSB-PA887136LA01HU diluted at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA887136LA01HU diluted at 1:400 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of HepG2 cells with CSB-PA887136LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
RIOK2 Antibodies
RIOK2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA887136LA01HU | RIOK2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA887136LB01HU | RIOK2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA887136LC01HU | RIOK2 Antibody, FITC conjugated | Human | |
| CSB-PA887136LD01HU | RIOK2 Antibody, Biotin conjugated | Human | ELISA |
RIOK2 Proteins
RIOK2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP887136HU CSB-EP887136HU CSB-BP887136HU CSB-MP887136HU CSB-EP887136HU-B |
Recombinant Human Serine/threonine-protein kinase RIO2 (RIOK2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |






