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RAPGEF1

Rap guanine nucleotide exchange factor 1 is a protein in humans that is encoded by RAPGEF1 gene. Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

RAPGEF1 Antibodies

RAPGEF1 for Homo sapiens (Human)

RAPGEF1 Proteins

RAPGEF1 Proteins for Homo sapiens (Human)



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