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PYDC1

Pyrin domain-containing protein 1 is a protein in humans that is encoded by PYDC1 gene. Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

PYDC1 Proteins

PYDC1 Proteins for Homo sapiens (Human)