PTPN6
PTPN6，全稱為蛋白酪氨酸磷酸酶非受體6型，是一種在人體中發(fā)揮重要作用的蛋白質(zhì)。它也被稱為HCP、PTP1C、SH-PTP1、Protein-tyrosine phosphatase SHP-1等。PTPN6在細(xì)胞信號(hào)傳導(dǎo)中扮演著關(guān)鍵角色，能夠調(diào)節(jié)多種細(xì)胞過程，包括細(xì)胞生長(zhǎng)、分化、有絲分裂周期和致癌轉(zhuǎn)化。該蛋白與免疫系統(tǒng)的功能密切相關(guān)，其異常可能與多種疾病有關(guān)，包括癌癥和自身免疫疾病。近年來，PTPN6在癌癥治療中的研究引起了廣泛關(guān)注，它可能成為潛在的生物標(biāo)志物和治療靶點(diǎn)。在藥物研發(fā)方面，針對(duì)PTPN6的藥物正在被開發(fā)，以用于治療與PTPN6相關(guān)的疾病。
熱銷產(chǎn)品
Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) (CSB-EP019043HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PTPN6 Antibody (CSB-PA019043HA01HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: PTPN6 antibody at 12μg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Raji whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 68, 64, 71 kDa
Observed band size: 68 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA019043HA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA019043HA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA019043HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PTPN6 Antibodies
PTPN6 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA019043HA01HU | PTPN6 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA019043HB01HU | PTPN6 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA019043HC01HU | PTPN6 Antibody, FITC conjugated | Human | |
| CSB-PA562160 | Phospho-PTPN6 (Tyr536) Antibody | Human,Mouse,Rat | ELISA,IHC,IF |
| CSB-PA561602 | PTPN6 (Ab-536) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA004085 | PTPN6 Antibody | Human | WB, ELISA |
| CSB-PA040102 | Phospho-PTPN6 (Y564) Antibody | Human,Monkey | WB, ELISA |
| CSB-PA040103 | Phospho-PTPN6 (Y536) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040104 | PTPN6 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA282609 | PTPN6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA150036 | PTPN6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
PTPN6 Proteins
PTPN6 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019043RA CSB-EP019043RA CSB-BP019043RA CSB-MP019043RA CSB-EP019043RA-B |
Recombinant Rat Tyrosine-protein phosphatase non-receptor type 6 (Ptpn6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTPN6 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019043HU CSB-BP019043HU CSB-MP019043HU CSB-EP019043HU-B |
Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019043HU | Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) | E.coli |
PTPN6 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP019043MO CSB-BP019043MO CSB-MP019043MO CSB-EP019043MO-B |
Recombinant Mouse Tyrosine-protein phosphatase non-receptor type 6 (Ptpn6) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
