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PTH1R

PTH1R,全稱為甲狀旁腺激素1型受體,也被稱為PTH/PTHrP受體或PTH1受體。該蛋白在骨骼發育和穩態中扮演重要角色,主要由甲狀旁腺激素(PTH)和甲狀旁腺激素相關肽(PTHrP)激活。PTH1R主要在成骨細胞中表達,通過調節骨代謝影響骨骼健康。與PTH1R相關的疾病包括骨質疏松癥和腎臟疾病。近年來,針對PTH1R的藥物研發取得了顯著進展,新型小分子激動劑藥物的開發為治療相關疾病提供了新的方向。

熱銷產品

Recombinant Human Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R), partial (Active) (CSB-MP018988HU)

驗證數據

CSB-MP018988HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP018988HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human PTH1R at 2 μg/ml can bind Anti-PTH1R recombinant antibody (CSB-RA018988MA1HU). The EC50 is 0.7813-1.048 ng/mL.

CSB-MP018988HU

PTH1R Recombinant Monoclonal Antibody (CSB-RA018988MA1HU) captured on Protein A Chip can bind Recombinant Human PTH1R protein with an affinity constant of 0.14 nM as detected by MetaSPR Assay (WeSPRTM 200).

PTH1R Recombinant Monoclonal Antibody (CSB-RA018988MA1HU)

驗證數據

CSB-RA018988MA1HU

The Binding Activity of Human PTH1R with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PTH1R(CSB-MP018988HU) at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC50 is 0.7813-1.048 ng/mL.

CSB-RA018988MA1HU

The Binding Activity of Rat Pth1r with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Rat Pth1r(CSB-MP018988RA2) at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC50 is 0.7384-1.203 ng/mL.

CSB-RA018988MA1HU

The Binding Activity of Macaca fascicularit PTH1R with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularit PTH1R(CSB-MP018988MOV4) at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC50 is 1.072 to 1.403 ng/mL.

CSB-RA018988MA1HU

The Binding Activity of Macaca fascicularit PTH1R with Anti-PTH1R recombinant antibody
Activity: Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularit PTH1R(CSB-MP018988MOV4) at 2 μg/mL can bind Anti-PTH1R recombinant antibody. The EC50 is 1.072 to 1.403 ng/mL.

PTH1R Antibodies

PTH1R for Homo sapiens (Human)

PTH1R Proteins

PTH1R Proteins for Rattus norvegicus (Rat)

PTH1R Proteins for Mus musculus (Mouse)

PTH1R Proteins for Sus scrofa (Pig)

PTH1R Proteins for Didelphis marsupialis virginiana (North American opossum)

PTH1R Proteins for Bos taurus (Bovine)

PTH1R Proteins for Pongo abelii (Sumatran orangutan)

PTH1R Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

PTH1R Proteins for Homo sapiens (Human)



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