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PRDX1

過氧化物氧還原蛋白酶1,簡稱PRDX1,是一種重要的細(xì)胞內(nèi)抗氧化蛋白,屬于谷胱甘肽過氧化物酶家族。它能夠催化還原性谷胱甘肽(GSH)與過氧化氫(H2O2)之間的氧化還原反應(yīng),從而清除細(xì)胞內(nèi)的過氧化物,保護(hù)細(xì)胞免受氧化損傷。PRDX1在多種生物過程中發(fā)揮重要作用,包括炎癥反應(yīng)、細(xì)胞增殖和分化等。研究表明,PRDX1的表達(dá)與多種疾病相關(guān),如癌癥、神經(jīng)退行性疾病和心血管疾病等。近年來,PRDX1在疾病診斷和治療中的應(yīng)用也引起了廣泛關(guān)注。例如,PRDX1的表達(dá)水平可以作為某些癌癥的生物標(biāo)志物,而針對PRDX1的藥物研發(fā)也取得了一定的進(jìn)展,例如,一些小分子化合物可以抑制PRDX1的活性,從而增強(qiáng)細(xì)胞的抗氧化能力,用于治療氧化損傷相關(guān)的疾病。

熱銷產(chǎn)品

Recombinant Human Peroxiredoxin-1(PRDX1) (CSB-EP018653HUb1)

驗證數(shù)據(jù)

CSB-EP018653HUb1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PRDX1 Recombinant Monoclonal Antibody (CSB-RA571559A0HU)

驗證數(shù)據(jù)

CSB-RA571559A0HU

Flow cytometric analysis of peroxiredoxin 1 expression in HepG2 cells using peroxiredoxin 1 antibody. Green, isotype control; red, peroxiredoxin 1.

CSB-RA571559A0HU

Western blotting analysis using peroxiredoxin 1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with peroxiredoxin 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.

PRDX1 Antibody (CSB-PA01165A0Rb)

驗證數(shù)據(jù)

CSB-PA01165A0Rb

Western blot
All lanes: PRDX1 antibody at 2µg/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa

CSB-PA01165A0Rb

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA01165A0Rb at dilution of 1:50

CSB-PA01165A0Rb

Immunofluorescent analysis of HepG2 cells using CSB-PA01165A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Peroxiredoxin-1(PRDX1) ELISA kit (CSB-EL018653HU)

驗證數(shù)據(jù)

CSB-EL018653HU 標(biāo)準(zhǔn)曲線

貨號:CSB-EL018653HU

規(guī)格:96T/48T

靈敏度:0.78 ng/mL

檢測范圍:3.12 ng/mL-200 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PRDX1 Antibodies

PRDX1 for Homo sapiens (Human)

PRDX1 for H, M, R

PRDX1 Proteins

PRDX1 Proteins for Gallus gallus (Chicken)

PRDX1 Proteins for Mus musculus (Mouse)

PRDX1 Proteins for Homo sapiens (Human)

PRDX1 Proteins for Bos taurus (Bovine)

PRDX1 Proteins for Gecko japonicus (Japanese gecko)

PRDX1 Proteins for Myotis lucifugus (Little brown bat)

PRDX1 Proteins for Rattus norvegicus (Rat)

PRDX1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

PRDX1 ELISA Kit

PRDX1 ELISA Kit for Homo sapiens (Human)

PRDX1 ELISA Kit for Mus musculus (Mouse)