PKMYT1
PKMYT1，蛋白全稱為膜相關酪氨酸/蘇氨酸蛋白激酶1，常見別名包括MYT1。這種蛋白是一種定位于細胞膜的激酶分子，核心作用是參與細胞分裂進程的精準調控——它通過對細胞周期關鍵蛋白的修飾，延緩細胞從DNA復制后期進入分裂階段，確保細胞在遺傳物質完全復制且無誤后再啟動分裂，維持細胞增殖的正常秩序。
PKMYT1活性異常時，細胞分裂的調控機制易失衡，進而推動腫瘤發生發展。比如在肺癌、乳腺癌等惡性腫瘤中，常能檢測到它的表達水平顯著升高，這會加速腫瘤細胞的無序增殖與擴散。目前針對它的靶向干預研究正逐步推進，部分小分子抑制劑已在臨床前實驗中展現潛力：這些化合物可特異性阻斷其功能，幫助恢復細胞周期節律，對腫瘤細胞產生抑制效果，為相關癌癥治療提供了新的潛在方向。
熱銷產品
PKMYT1 Antibody (CSB-PA16029A0Rb)
驗證數據
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA16029A0Rb at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA16029A0Rb at dilution of 1:100
PKMYT1 Antibodies
PKMYT1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA16029A0Rb | PKMYT1 Antibody | Human | ELISA, IHC |
| CSB-PA018073GA01HU | PKMYT1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA729561 | Phospho-PKMYT1 (Ser83) Antibody | Human | ELISA,IHC |
| CSB-PA003356 | PKMYT1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA070226 | Phospho-PKMYT1 (S83) Antibody | Human | IHC, ELISA |
| CSB-PA254680 | PKMYT1 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA955430 | PKMYT1 Antibody | Human,Mouse | ELISA,WB,IHC |
PKMYT1 Proteins
PKMYT1 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP849597XBE CSB-EP849597XBE CSB-BP849597XBE CSB-MP849597XBE CSB-EP849597XBE-B |
Recombinant Xenopus laevis Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (pkmyt1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PKMYT1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP858720HU CSB-EP858720HU CSB-BP858720HU CSB-MP858720HU CSB-EP858720HU-B |
Recombinant Human Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PKMYT1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP866844MO CSB-EP866844MO CSB-BP866844MO CSB-MP866844MO CSB-EP866844MO-B |
Recombinant Mouse Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Pkmyt1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
