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PCCA

PCCA全稱為丙酰輔酶A羧化酶α亞基,也被稱為丙酰輔酶A羧化酶α鏈。該蛋白是丙酰輔酶A羧化酶復合物的重要組成部分,該復合物在丙酸代謝中發揮關鍵作用。PCCA蛋白的缺陷會導致丙酸血癥,這是一種罕見的遺傳代謝疾病。目前,針對丙酸血癥的治療主要依賴于肝移植,而mRNA療法如mRNA-3927的研發為治療該疾病提供了新的希望。此外,PCCA蛋白的研究也為開發針對其他代謝性疾病的藥物提供了潛在靶點。

熱銷產品

Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) (CSB-EP017522HU)

驗證數據

CSB-EP017522HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PCCA Antibody (CSB-PA017522LA01HU)

驗證數據

CSB-PA017522LA01HU

Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate, Hela whole cell lysate
All lanes: PCCA antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 81, 78, 76 kDa
Observed band size: 81 kDa

CSB-PA017522LA01HU

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA017522LA01HU at dilution of 1:100

CSB-PA017522LA01HU

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA017522LA01HU at dilution of 1:100

PCCA Antibodies

PCCA for Homo sapiens (Human)

PCCA Proteins

PCCA Proteins for Homo sapiens (Human)