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PAK2

PAK2,全稱為p21 (RAC1) activated kinase 2,是一種重要的蛋白酶激酶,在細胞信號傳導通路中扮演著關鍵角色。該蛋白屬于蛋白激酶Cdc42/Rac-activated kinase (PAK) 家族,與細胞運動、增殖等多種生物學過程密切相關。PAK2通過與Cdc42和Rac蛋白結合而被激活,參與細胞的遷移和測定。在細胞增殖方面,PAK2通過激活細胞周期相關基因和細胞核受體,促進細胞的增殖。此外,PAK2在細胞凋亡過程中也發揮著重要作用,可調控多種信號通路,對程序性細胞的調控至關重要。PAK2重組蛋白作為一種生物制藥產品,在生物學研究和醫學應用中具有廣闊的應用前景。

熱銷產品

PAK2 Recombinant Monoclonal Antibody (CSB-RA592787A0HU)

驗證數據

CSB-RA592787A0HU

Western Blot
Positive WB detected in: 293 whole cell lysate, Jurkat whole cell lysate, Raji whole cell lysate, Mouse brain tissue, Rat brain tissue
All lanes: PAK2 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59 kDa
Observed band size: 59 kDa

CSB-RA592787A0HU

Overlay histogram showing HepG2 cells stained with CSB-RA592787A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.

CSB-RA592787A0HU

Immunoprecipitating PAK2 in Raji whole cell lysate
Lane 1: Rabbit control IgG instead of CSB-RA592787A0HU in Raji whole cell lysate. For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-RA592787A0HU(2μg)+ Raji whole cell lysate(500μg)
Lane 3: Raji whole cell lysate (10μg)

PAK2 Antibodies

PAK2 for Homo sapiens (Human)

PAK2 Proteins

PAK2 Proteins for Homo sapiens (Human)

PAK2 Proteins for Oryctolagus cuniculus (Rabbit)

PAK2 Proteins for Rattus norvegicus (Rat)

PAK2 Proteins for Mus musculus (Mouse)



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