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NR1I2

NR1I2,全稱為核受體亞家族1組I成員2,也被稱為PXR、NR1I2、Orphan nuclear receptor PAR1、Orphan nuclear receptor PXR、Pregnane X receptor、Steroid and xenobiotic receptor、SXR等。它是一種核受體,作為多功能轉錄因子,能夠被多種內源性和外源性化合物激活。NR1I2在調節物質代謝和分泌的基因中發揮關鍵作用,對利福平、金絲桃素、古古林、colupulone、異黃酮、孕烯醇酮和黃體酮等配體作出反應。NR1I2的研究對于理解肝臟代謝和藥物代謝具有重要意義,其異常可能與多種疾病相關,如肝癌等。在藥物研發方面,NR1I2作為潛在的藥物靶點,其相關研究有助于開發新的治療策略。

熱銷產品

Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) (CSB-EP016048HU)

驗證數據

CSB-EP016048HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-EP016048HU

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016048HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1I2.

CSB-EP016048HU

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016048HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1I2.

NR1I2 Antibody (CSB-PA016048ESR1HU)

驗證數據

CSB-PA016048ESR1HU

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA016048ESR1HU at dilution of 1:100

NR1I2 Antibodies

NR1I2 for Homo sapiens (Human)

NR1I2 Proteins

NR1I2 Proteins for Homo sapiens (Human)

NR1I2 Proteins for Mus musculus (Mouse)

NR1I2 Proteins for Macaca mulatta (Rhesus macaque)

NR1I2 Proteins for Rattus norvegicus (Rat)