MTCH2
MTCH2，全稱為線粒體外膜蛋白2，是一種參與細胞能量代謝的重要蛋白。它主要位于線粒體外膜，負責將細胞質中合成的蛋白轉運至線粒體外膜。MTCH2的常見別名包括MIMP、SLC25A50等。研究發現，MTCH2在多種細胞過程中發揮關鍵作用，包括細胞凋亡、線粒體功能調控等。在癌癥治療中，MTCH2成為了一個重要的靶點。研究表明，MTCH2在非小細胞肺癌和去勢抵抗性前列腺癌中過表達，沉默或敲除MTCH2可以抑制腫瘤細胞的生長和轉移，并誘導細胞凋亡?；谶@一發現，針對MTCH2的藥物研發正在積極開展中，有望為癌癥患者帶來新的治療選擇。此外，MTCH2還與AML等疾病相關，進一步研究其功能將為疾病治療提供新的思路。
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA083456(MTCH2 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Human testis tissue, K562 cells, PC3 cells, human liver cancer tissue, hela cells, Primary antibody: CSB-PA083456(MTCH2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
MTCH2 Antibodies
MTCH2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015133GA01HU | MTCH2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA083456 | MTCH2 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA897586LA01HU | MTCH2 Antibody | Human | ELISA, IHC |
| CSB-PA897586LB01HU | MTCH2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA897586LC01HU | MTCH2 Antibody, FITC conjugated | Human | |
| CSB-PA897586LD01HU | MTCH2 Antibody, Biotin conjugated | Human | ELISA |
MTCH2 Proteins
MTCH2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP897586HU1 CSB-EP897586HU1 CSB-BP897586HU1 CSB-MP897586HU1 CSB-EP897586HU1-B |
Recombinant Human Mitochondrial carrier homolog 2 (MTCH2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF897586HU | Recombinant Human Mitochondrial carrier homolog 2 (MTCH2) | in vitro E.coli expression system |
