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MELTF

MELTF,全稱為melanotransferrin,別名包括MTf、MFI2、MTF1、CD228和MAP97。該蛋白是一種細胞表面糖蛋白,主要表達于黑素瘤細胞,同時也在唾液腺、腎臟等多種組織中存在。MELTF蛋白與轉鐵蛋白超家族成員具有序列相似性和鐵結合特性,但其在鐵代謝中的具體作用尚未明確。研究表明,MELTF蛋白可能參與腫瘤細胞的生長和轉移過程,并可能與某些癌癥的發生發展相關。目前,針對MELTF蛋白的藥物研發尚處于早期階段,但已有研究顯示其可能成為癌癥治療的潛在靶點。例如,有研究探索了MELTF蛋白在黑色素瘤細胞中的表達和功能,并發現其可能參與腫瘤細胞的侵襲和轉移。此外,還有研究報道了MELTF蛋白在胃癌、結直腸癌等癌癥組織中的高表達,提示其可能成為癌癥診斷和治療的新的生物標志物和治療靶點。未來,隨著對MELTF蛋白研究的深入,有望開發出針對該蛋白的特異性藥物,為癌癥患者提供新的治療選擇。

熱銷產品

Recombinant Human Melanotransferrin (MELTF) (Active) (CSB-MP013754HU1)

驗證數據

CSB-MP013754HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP013754HU1

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MELTF at 2 μg/ml can bind Anti-MELTF recombinant antibody (CSB-RA013754MA1HU). The EC50 is 0.3476-0.4529 ng/mL.

CSB-MP013754HU1

The purity of MELTF was greater than 95% as determined by SEC-HPLC

Recombinant Human Melanotransferrin (MELTF) (CSB-EP013754HU)

驗證數據

CSB-EP013754HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MELTF Antibody (CSB-PA013754LA01HU)

驗證數據

CSB-PA013754LA01HU

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate
All lanes: MELTF antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 81, 33 kDa
Observed band size: 81 kDa

CSB-PA013754LA01HU

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA013754LA01HU at dilution of 1:100

CSB-PA013754LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA013754LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Melanotransferrin(MFI2) ELISA kit (CSB-EL013754HU)

驗證數據

CSB-EL013754HU 標準曲線

貨號:CSB-EL013754HU

規格:96T/48T

靈敏度:0.039 ng/mL

檢測范圍:0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

MELTF Antibodies

MELTF for Homo sapiens (Human)

MELTF Proteins

MELTF Proteins for Homo sapiens (Human)

MELTF Proteins for Oryctolagus cuniculus (Rabbit)

MELTF Proteins for Mus musculus (Mouse)

MELTF ELISA Kit

MELTF ELISA Kit for Homo sapiens (Human)



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