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LBR

LBR,全名為lamin B受體,也被稱為核纖層蛋白B受體。它在細胞核膜的內層,負責將核纖層和異染色質錨定在核膜上,對染色質和核纖層蛋白B之間的相互作用至關重要。LBR蛋白在膽固醇合成過程中也扮演著關鍵角色。LBR基因的突變與遺傳性骨骼發育不良和Greenberg骨骼發育不良等疾病相關。目前,針對LBR蛋白的藥物研發主要集中在開發抗體和siRNA等治療方法,以治療相關疾病。

熱銷產品

LBR Antibody (CSB-PA070468)

驗證數據

CSB-PA070468

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA070468(LBR Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA070468

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA070468(LBR Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes

LBR Antibodies

LBR for Homo sapiens (Human)

LBR Proteins

LBR Proteins for Homo sapiens (Human)