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L3T4

L3T4,也被稱為CD4分子,是T淋巴細胞表面的一種關鍵受體,它在T細胞的發育、激活以及免疫應答中起到核心作用。結構上,L3T4由胞外區、跨膜區和胞內區組成,能夠特異性地與主要組織相容性復合體(MHC)II類分子結合,這對于T細胞識別抗原至關重要。在信號通路上,當L3T4與MHC II類分子結合后,它會觸發一系列信號通路的激活,包括酪氨酸激酶途徑、磷脂酶C途徑和鈣離子途徑等,這些通路的激活促進T細胞的增殖、分化和效應功能的發揮。在功能上,L3T4不僅參與T細胞對“自我”和“非我”的識別,還在T細胞分化為輔助性T細胞(Th細胞)的過程中發揮關鍵作用,并調節免疫應答的強度和方向,以維持機體免疫平衡。

熱銷產品

CD4 Recombinant Monoclonal Antibody (CSB-RA004935A0HU)

驗證數據

CSB-RA004935A0HU

Western Blot
Positive WB detected in Jurkat whole cell lysate
All lanes CD4 antibody at 0.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 KDa
Observed band size: 55 KDa

CSB-RA004935A0HU

IHC image of CSB-RA004935A0HU diluted at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-RA004935A0HU

IHC image of CSB-RA004935A0HU diluted at 1:100 and staining in paraffin-embedded human spleen tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

L3T4 Antibodies

L3T4 for Homo sapiens (Human)

L3T4 for H, M, R

L3T4 Proteins

L3T4 Proteins for Homo sapiens (Human)

L3T4 Proteins for Homo sapiens(Human)

L3T4 ELISA Kit

L3T4 ELISA Kit for Homo sapiens (Human)



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