KMT2A
KMT2A，即賴氨酸特異性組蛋白甲基轉(zhuǎn)移酶2A，別名MLL1、HYPB、TRXR1。它是一種由KMT2A基因編碼的酶，屬于非典型組蛋白甲基轉(zhuǎn)移酶家族成員。KMT2A的作用機(jī)制是通過催化組蛋白H3第4位賴氨酸的二甲基化（H3K4me2），參與調(diào)控基因的表達(dá)，特別是在細(xì)胞分化和發(fā)育過程中。KMT2A在細(xì)胞增殖、神經(jīng)發(fā)育、造血和腫瘤發(fā)生等生物學(xué)過程中具有重要作用。其功能異常與遺傳性疾病和癌癥的發(fā)生發(fā)展有關(guān)，是藥物開發(fā)和疾病治療中的潛在靶點(diǎn)。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
KMT2A Antibodies
KMT2A for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA612015 | KMT2A Antibody | Human,Mouse,Rat | IHC,ELISA |
KMT2A Proteins
KMT2A Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP014627MO CSB-EP014627MO CSB-BP014627MO CSB-MP014627MO CSB-EP014627MO-B |
Recombinant Mouse Histone-lysine N-methyltransferase MLL (Mll), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
