IL3

IL3，即白細胞介素3，別名Interleukin-3、MCGF。IL-3主要由活化的T細胞和NK細胞產生，此外，IL-1激活的人內皮細胞、IgE激活的小鼠肥大細胞和胎盤細胞等也能產生IL-3。IL-3的作用機制主要通過與其受體結合并觸發細胞內信號傳導過程來實現。IL-3與其受體α鏈（IL-3Rα）結合后，會進一步與β鏈（IL-3Rβ，CD131）結合，形成異源二聚體或寡聚體，從而激活受體相關的Janus激酶（JAK），主要是JAK2。激活的JAK2募集STAT5并介導其磷酸化，磷酸化的STAT5進入細胞核，誘導下游效應基因的轉錄。此外，IL-3還激活Ras-MAPK和磷酸肌醇3-激酶（PI3K）通路。IL-3是一種重要的造血生長因子，對多種細胞類型的發育起著關鍵作用，包括粒細胞、單核細胞、巨噬細胞、嗜酸性粒細胞、嗜堿性粒細胞和肥大細胞。IL-3還參與免疫調節、炎癥反應以及血液系統疾病的治療。

熱銷產品

Recombinant Human Interleukin-3 (IL3) (Active) (CSB-MP011652HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is 0.3149 to 1.023 ng/mL.

Recombinant Human Interleukin-3 (IL3) (Active) (CSB-EP011652HUc7)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is 5.972-17.16 ng/mL.

IL3 Antibody

IL3 Protein

IL3 ELISA Kit

IL3 Antibodies

IL3 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA011652GA01HU	IL3 Antibody	Human	ELISA,WB
CSB-PA06725B0Rb	IL3 Antibody, HRP conjugated	Human	ELISA
CSB-PA06725A0Rb	IL3 Antibody	Human	ELISA, IHC
CSB-PA011652ESR1HU	IL3 Antibody	Human	ELISA, IHC
CSB-PA196621	IL3 Antibody	Human,Mouse	ELISA,WB

IL3 Proteins

IL3 Proteins for Macaca mulatta (Rhesus macaque)

產品貨號	產品名稱	來源
CSB-YP011652MOW CSB-EP011652MOW CSB-BP011652MOW CSB-MP011652MOW CSB-EP011652MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Interleukin-3 (IL3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001981MOW	Recombinant Rhesus Macaque Interleukin-3 protein (IL3)	E.Coli

IL3 Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP011652BO CSB-BP011652BO CSB-MP011652BO CSB-EP011652BO-B	Recombinant Bovine Interleukin-3 (IL3)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL3 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-EP011652MO CSB-BP011652MO CSB-EP011652MO-B	Recombinant Mouse Interleukin-3 (Il3)	E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-AP003291MO	Recombinant Mouse Interleukin-3 protein (Il3), partial	E.Coli

IL3 Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP011652RA CSB-EP011652RA CSB-BP011652RA CSB-MP011652RA CSB-EP011652RA-B	Recombinant Rat Interleukin-3 (Il3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL3 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP011652HU CSB-BP011652HU CSB-EP011652HU-B	Recombinant Human Interleukin-3 (IL3)	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP011652HU	Recombinant Human Interleukin-3 (IL3)	E.coli
CSB-AP001701HU	Recombinant Human Interleukin-3 protein (IL3)(P27S) (Active)	E.Coli
CSB-EP011652HUc7	Recombinant Human Interleukin-3 (IL3) (Active)	E.coli
CSB-AP004521HU	Recombinant Human Interleukin-3 (IL3) (Active)	Mammalian cell
CSB-AP004531HU	Recombinant Human Interleukin-3 (IL3) (Active)	E.coli
CSB-AP005821HU	Recombinant Human Interleukin-3 (IL3), partial (Active) (GMP)	E.Coli
CSB-MP011652HU-WD	Recombinant Human Interleukin-3 (IL3) (Active)	Mammalian cell
CSB-YP011652HUd7	Recombinant Human Interleukin-3 (IL3) (Active)	Yeast
CSB-MP011652HU	Recombinant Human Interleukin-3 (IL3) (Active)	Mammalian cell

IL3 Proteins for Saguinus oedipus (Cotton-top tamarin)

產品貨號	產品名稱	來源
CSB-YP011652SWB CSB-EP011652SWB CSB-BP011652SWB CSB-MP011652SWB CSB-EP011652SWB-B	Recombinant Saguinus oedipus Interleukin-3 (IL3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL3 Proteins for Hylobates lar (Common gibbon)

產品貨號	產品名稱	來源
CSB-YP011652HXW CSB-EP011652HXW CSB-BP011652HXW CSB-MP011652HXW CSB-EP011652HXW-B	Recombinant Hylobates lar Interleukin-3 (IL3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL3 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

產品貨號	產品名稱	來源
CSB-YP632965CYL CSB-EP632965CYL CSB-BP632965CYL CSB-MP632965CYL CSB-EP632965CYL-B	Recombinant Callithrix jacchus Interleukin-3 (IL3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL3 Proteins for Pan troglodytes (Chimpanzee)

產品貨號	產品名稱	來源
CSB-YP637919EQV CSB-EP637919EQV CSB-BP637919EQV CSB-MP637919EQV CSB-EP637919EQV-B	Recombinant Pan troglodytes Interleukin-3 (IL3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產品貨號	產品名稱	來源
CSB-YP860200DO CSB-EP860200DO CSB-BP860200DO CSB-MP860200DO CSB-EP860200DO-B	Recombinant Dog Interleukin-3 (IL3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli